Transgenics
Canadian Mouse Mutant Repository (Mount Sinai Hospital, Hospital for Sick Children, University Health Network and St. Michael's Hospital). This facility houses a central repository for the physical archive of cryopreserved ES cells, spermatozoa, ova, embryos, and tissue DNA generated by Canada's mouse genome effort. The CMMR also collects and stores the somatic tissue from these mouse models using a variety of formats (fixed, embedded, and glass-slide mounted).
Mouse Transgenic Centre (Centre for Addiction and Mental Health). The Transgenic Centre breeds and maintains transgenic mice strains for CAMH researchers. The facility can also help scientists create their own transgenic mice strains or employ viral-mediated gene transfer experiments.
Toronto Centre for Phenogenomics (Mount Sinai Hospital, Hospital for Sick Children, St. Michael's Hospital and University Health Network). The Centre is an innovative, scientific collaboration between four research hospitals to operate a centralized, state-of-the-art mouse facility for genetic research involving generation of mutant mice, physiological phenotyping, behavioural analysis, imaging, pathology and cryopreservation for storage and preservation.
The Transgenic Core Facility (Mount Sinai Hospital). The Transgenic Core Facility offers the following services: 1) transgenic production, 2) generation of chimeras, 3) mouse embryo cryopreservation and 4) mouse embryo shipment.
Transgenic and Gene Targeting Facility (Sunnybrook Health Sciences Centre). The Facility has the following services: pronuclear microinjection, embryo aggregation, blastocyst injection, embryo and cryopreservation.