Facilities

An introductory short list of our members’ facilities, centers and programs associated with specific research areas is given below. Please see Members section for complete listings

Proteomics

The Advanced Protein Technology Centre (Hospital for Sick Children). provides protein research services including amino acid analysis, peptide sequencing and synthesis and mass spectrometry.

NMR Services (University of Toronto). Located at the heart of downtown University of Toronto campus the NMR services provide both academic and non-academic services. The centre has 500 MHz, 400 MHz, 300 MHz and 200 MHz equipment for performing high resolution liquid NMR. The facility is also equipped with the latest DSX 400 and DSX 200 equipment for performing solid state NMR. Most of our equipment is operated hands-on by trained graduate and undergraduate students. Staff are on hand to advise and train students, to run more complicated experiments and to run outside requests.

Ontario Centre for Structural Proteomics (University Health Network).  Research at the centre focuses on using X-ray crystallography and NMR spectroscopy to perform structural proteomics studies.

Proteomics Core Facility (Sunnybrook Health Sciences Centre). Differential proteomics, protein analysis, in-gel and in-solution protein identification/characterization, peptide synthesis, mass spectrometers, Biacore 3000 access for measurement of binding constants and sample fractionation by HPLC.

Proteomics and Mass Spectrometry Centre (University of Toronto). The Centre's mandate is to provide mass spectrometry services for academic as well as industrial clients. The personnel of PMSC help users to choose and design experiments, to execute experiments using the appropriate instruments, to obtain data required by the users, and to interpret the results. The Centre also provides instruction and training for graduate students and postdoctoral fellows for the use of different mass spectrometry approaches.

Proteomics Research Centre (University of Toronto). The focus and long-term objectives of the Proteomics Research Center (PRC), are to develop a fully integrated experimental framework for researchers to systematically address the complexities of protein function and cellular networks using advanced and complimentary experimental approaches and technologies.

Structural Genomics Consortium (University of Toronto). The Consortium is a not-for-profit company that aims to determine the three dimensional structures of proteins of medical relevance, and place them in the public domain without restriction. Announced in April 2003, this initiative receives funding from Canadian and British sponsors from both the public and private sectors - the Wellcome Trust, GlaxoSmithKline, Genome Canada, the Ontario Research and Development Challenge Fund, the Ontario Innovation Trust and the Canadian Institutes of Health Research. In 2005, a consortium of Swedish sponsors (VINNOVA, SSF, KAW and KI) provided funds to the SGC and a Swedish node was launched at the Karolinska Institute.

The Toronto Centre for Phenogenomics. The TCP is an innovative, scientific collaboration between four research hospitals to operate a centralized, state-of-the-art research-enabling mouse facility. They conduct and support genetic research involving generation of mutant mice, physiological phenotyping, behavioural analysis, imaging, pathology and cryopreservation for storage and distribution.

top