Facilities
An introductory short list of our members’ facilities, centers and programs associated with specific research areas is given below. Please see Members section for complete listings
Genomics
Analytical Genetics Technology Centre (University Health Network). AGTC's 5,000 sq. ft., state-of-the-art, genotyping facility operates under cGLP guidelines. Sample handling and processing are fully automated and are performed by advanced robotics that includes Biomek FX, ABI 6700 liquid handling systems, and RoboDesign plotting robot which allow for improved precision and throughputs in excess of 5,000 SNP genotypes per day.
The facility is equipped with a number of platforms for high throughput SNP identification and genotyping including the Affymetrix GeneChip system, Sequenom MassARRAY? and the ABI PRISM? 7900HT Sequence Detection System.
The Canadian Drosophila Microarray Centre (University of Toronto). The CDMC is a microarray facility for Canadian and international academic scientists working with Drosophila. There are two main objectives of the CDMC: (1) To produce and provide Drosophila DNA microarrays on glass slides and (2) To provide a microarray experiment service facility where the scientist provides samples of RNA (or DNA), and the CDMC performs the labelling, hybridization and scanning.
The Centre for Applied Genomics - TCAG (The Hospital for Sick Children) provides infrastructure to facilitate a wide variety of genomics research. The Centre's services are available to researchers in the academic, government or private sectors. TCAG supports Genome Canada projects as well as hundreds of other researchers in Ontario, Canada and worldwide.
Centre for Genomic Medicine (Mount Sinai Hospital). Core facilities of tools that expedite translational research within the Mount Sinai Hospital. Such tools include, for example, clinical informatics tools that facilitate the rapid integration of clinical genomic/proteomic data and statistical tools for the integrated analysis of clinical and genetic data. The centre also focuses on improving core facilities such as SNP genotyping required for genomic medicine research.
DNA Sequencing Facility (University Health Network). High through-put DNA sequencing on Beckman Coulter capillary sequencers, Offers services to local academic or industry customers.
Epigenetics Centre (Centre for Addiction and Mental Health). Innovative research related to how inherited, as well as environmental factors, like diet, stress and maternal nutrition, can change gene function without changing the DNA sequence.
Microarray Centre (University Health Network). Provides high quality microarrays, technical support and service to Canadian researchers.
Prosserman Centre for Health Research (Mount Sinai Hospital). Investigators lead innovative genetic and molecular epidemiologic research, whereby new molecular biological concepts and methods are applied in studies of individuals and human populations. These studies focus on complex diseases in human populations and aim to provide better insights into the combined genetic and environmental determinants of disease, to assess the impact of these factors on disease, risk, and to evaluate strategies for disease control.
The Samuel Lunenfeld Research Institute Microarray Facility (Mount Sinai Hospital). The microarray facility provides services and a variety of microarray products including mouse, human, yeast, C. elegans and zebrafish arrays. Arrays are available for sale and consulting and custom service is offered.
The Toronto Centre for Phenogenomics. The TCP is an innovative, scientific collaboration between four research hospitals to operate a centralized, state-of-the-art research-enabling mouse facility. They conduct and support genetic research involving generation of mutant mice, physiological phenotyping, behavioural analysis, imaging, pathology and cryopreservation for storage and distribution.